Flex Equine Plus
Vetpro 3 Horses Flex-Equine Plus is a nutriceutical (100% natural) supplement formulated for feeding to horses with impaired joint function. It helps to maintain cartilage elasticity and aids in the repair of damaged cartilage. It is an improved development of Flex Equine as it also contains Undenatured Collagen Type ll, which has been scientifically proven to increase the already established benefits of our formula with Glucosamine, mixed Glycosaminoglycans (Chondroitin), Manganese Ascorbate, Copper Chelate, Zinc Chelate and Gelatin.
The mixed Glycosaminoglycans (GAGS) include Chondroitin Sulphate and Keratin Sulphate. Both these are used in the cartilage repair process. The Manganese Ascorbate is necessary for the conversion of the Glucosamine to GAGs to occur. Note Glucosamine alone is not effective - it needs to be in a formulation that ensures the required dose is not absorbed by the liver, but reaches the cartilage. Science has also shown that the combination of Glucosamine and Chondroitin provides a more effective response than either actives alone.
Undenatured Collagen Type ll is a new discovery that was determined to be effective in relieving osteoarthritis in humans but has now been independently scientifically tested on horses and showed remarkable positive responses. Flex Equine Plus contains 555mg – higher than the 450mg shown to be effective in the science trials.
Copper and Zinc are important trace elements that are essential for cartilage repair and maintenance. 3 Horses Flex-Equine Plus uses these minerals in the latest chelated form (glycinated) which means they are absorbed quickly and efficiently from the gut.
The gelatin in the formula includes high levels of Glycine and Proline, both of which are important components of collagen, the protein found in the cartilage matrix and again science has shown that gelatin improves the homeostasis of those amino acids required for cartilage synthesis.
Vetpro Flex Equine Plus contains the recommended amounts of the actives to be effective in improving joint elasticity and joint repairs. It puts the spring back into the horse and can assist to prolong the competitive life of the horse.
Active Ingredients per 30 gm dose:
Glucosamine Sulphate 12 g Undenatured Type ll Collagen 555 mg
Mixed Glycosaminoglycans 1.8gm Manganese Ascorbate 3.6 mg
Copper Chelate 13.4 mg Zinc Chelate 25.9 mg
Gelatin 15.2 gm
Loading Dose (first 4-6 weeks) Maintenance Dose:
Horses (450-500kg) 26-30gm Horses 13-15gm
Ponies (225-350kg) 13-20gm Ponies 7.5-10gm
Available in 500gm, 1Kg, 2Kg packs
Science on the active ingredients:
Therapeutic efficacy of undenatured type-II collagen (UC-II) in comparison to glucosamine and chondroitin in arthritic horses.
The Effect of Glucosamine and Chondroitin on Stressed Equine Cartilage Explants. R.S.A Harlan MS, R.C.A Haut PhD, M.W.A. Orth PhD
Effects of Chondroitin and Glucosamine Sulfate in a Dietary Bar Formulation on Inflammation,0 Interleukin-1CEB2, Matrix Metalloprotease-9, and Cartilage Damage in Arthritis. M. Chou*,Nathalie Vergnolle ,Jason 0 J. McDougall,John L. Wallace,Stephanie Marty,Val Teskey and AndreG. Buret.
Effects of glucosamine hydrochloride and chondroitin sulphate, alone and in combination, on normal and interleukin-1 conditioned equine articular cartilage explant metabolism. Dechant JE, Baxter GM, Frisbie DD, Trotter GW, McIlwraith CW
Effects of Oral Glucosamine and Chondroitin Sulfates Supplementation on Frequency of
Intra-articular Therapy of the Horse Tarsus Martha R. Rodgers, VMD
Role of glucosamine in the treatment for osteoarthritis
Jean-Yves Reginster • Audrey Neuprez •Marie-Paule Lecart • Nathalie Sarlet •Olivier Bruyere
Study of gelatin supplemented diet on amino acid homeostasis in the horse. M. Coenen, K. Appelt, A. Niemeyer,I. Vervuert
EFSA Journal 2010;8(10):1808 Scientific Opinion on the substantiation of health claims related to manganese contribution to normal formation of connective tissue (ID 404) Contribution to normal formation of connective tissue
Studies on the Role of Manganese in Bone Formation R. M. Leach, JR. Andanna-marie Muenster